1.1 This practice covers a procedure by which the irritancy of a biomaterial may be assessed through contact with abraded and intact skin of rabbits.
1.2 The results of this practice depend upon the effectiveness with which contact between the skin and the test material is established and maintained. Because of the operator technique included in performing this test, it is important that the test be performed by personnel with appropriate training.
1.3 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.
1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.
ASTM F719-81(2012) Referenced Document
ASTM F619 Standard Practice for Extraction of Medical Plastics
ASTM F719-81(2012) history
2020ASTM F719-20e1 Standard Practice for Testing Materials in Rabbits for Primary Skin Irritation
2020ASTM F719-20 Standard Practice for Testing Materials in Rabbits for Primary Skin Irritation
1981ASTM F719-81(2012) Standard Practice for Testing Biomaterials in Rabbits for Primary Skin Irritation
1981ASTM F719-81(2007)e1 Standard Practice for Testing Biomaterials in Rabbits for Primary Skin Irritation
1981ASTM F719-81(2007) Standard Practice for Testing Biomaterials in Rabbits for Primary Skin Irritation
1981ASTM F719-81(2002)e1 Standard Practice for Testing Biomaterials in Rabbits for Primary Skin Irritation
1981ASTM F719-81(2002) Standard Practice for Testing Biomaterials in Rabbits for Primary Skin Irritation
1981ASTM F719-81(1996)e1 Standard Practice for Testing Biomaterials in Rabbits for Primary Skin Irritation