This International Standard provides criteria for quality assurance and quality control, evaluation of the performance and the accreditation of biological dosimetry by cytogenetic service laboratories.
This International Standard addresses
a) the confidentiality of personal information, for the customer and the service laboratory,
b) the laboratory safety requirements,
c) the calibration sources and calibration dose ranges useful for establishing the reference dose-effect curves allowing the dose estimation from chromosome aberration frequency, and the minimum detection levels,
d) the scoring procedure for unstable chromosome aberrations used for biological dosimetry,
e) the criteria for converting a measured aberration frequency into an estimate of absorbed dose,
f) the reporting of results,
g) the quality assurance and quality control,
h) informative annexes containing examples of a questionnaire, instructions for customers, a data sheet for recording aberrations and a sample report.
ISO 19238:2004 history
2023ISO 19238:2023 Radiological protection — Performance criteria for service laboratories performing biological dosimetry by cytogenetics — Dicentric assay
2014ISO 19238:2014 Radiological protection - Performance criteria for service laboratories performing biological dosimetry by cytogenetics
2011ISO 19238:2011 Radiological protection — Performance criteria for service laboratories performing biological dosimetry by cytogenetics — Dicentric assay
2004ISO 19238:2004 Radiation protection - Performance criteria for service laboratories performing biological dosimetry by cytogenetics