T/SXITS 0003-2021 Determination of 8 Antifungal Components in Disinfectant Cream by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (English Version)
1. Specifies the principles, reagents and materials, instruments and equipment, analysis steps, result expression, precision, detection limit and quantification of high performance liquid chromatography-tandem mass spectrometry for 8 antifungal chemicals in Xiaozhengzi Cream limit. 2. Applicable to 8 antifungal chemicals in Xiaozhengzi Cream: miconazole, econazole, ketoconazole, griseofulvin, bifonazole, naftifine, clotrimazole, and terbinafine Qualitative and quantitative determination. 3. When the sample size is 0.5g and the fixed volume is 50mL, the detection limit of griseofulvin is 140μg/kg and the limit of quantification is 400μg/kg; clotrimazole, ketoconazole, terbinafine, and The detection limit of conazole is 70 μg/kg, and the limit of quantitation is 200 μg/kg; the detection limit of bifonazole, miconazole, and naftifine is 30 μg/kg, and the limit of quantification is 100 μg/kg.
T/SXITS 0003-2021 history
2021T/SXITS 0003-2021 Determination of 8 Antifungal Components in Disinfectant Cream by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry