API PUBL 33-32800-1986
MUTAGENICITY OF API 83-15 HEAVY NAPHTHENIC DISTILLATE (CAS 64742-52-5) IN A MOUSE LYMPHOMA MUTATION ASSAY

Standard No.

API PUBL 33-32800-1986

Release Date

1986

Published By

API - American Petroleum Institute

Latest

API PUBL 33-32800-1986

Scope

OBJECTIVE: The mouse lymphoma forward mutation assay evaluates a test article's mutagenic potential in a specific locus mutation assay using mammalian cells. The objective of the assay is to determine the ability of a test article to induce forward mutations at the thymidine kinase (TK) locus as assayed by colony growth of L5178Y TK+/- mouse lymphoma cells in the presence of 5-trifluorothymidine (TFT).

API PUBL 33-32800-1986 history

• 1986 API PUBL 33-32800-1986 MUTAGENICITY OF API 83-15 HEAVY NAPHTHENIC DISTILLATE (CAS 64742-52-5) IN A MOUSE LYMPHOMA MUTATION ASSAY