BS ISO 21243:2022 Radiation protection. Performance criteria for laboratories performing initial cytogenetic dose assessment of mass casualties in radiological or nuclear emergencies. General principles and application to dicentric assay
1 Scope
The purpose of this document is to give an overview of the minimum requirements for
performing the dicentric assay with quality control measures using mitogen stimulated
peripheral blood lymphocytes for initial assessment of individuals involved in a mass
casualty scenario. The dicentric assay is the use of chromosome damage to quickly
estimate approximate radiation doses received by individuals in order to supplement
the early clinical categorization of casualties.
This document focuses on the organizational and operational aspects of applying the
dicentric assay in an initial assessment mode. The technical aspects of the dicentric
assay can be found in ISO 19238.
This document is applicable either to an experienced biological dosimetry laboratory working alone or to a network of collaborating laboratories (as defined in Clause 7).
BS ISO 21243:2022 history
2022BS ISO 21243:2022 Radiation protection. Performance criteria for laboratories performing initial cytogenetic dose assessment of mass casualties in radiological or nuclear emergencies. General principles and application to dicentric assay
2008BS ISO 21243:2008 Radiation protection - Performance criteria for laboratories performing cytogenetic triage for assessment of mass casualties in radiological or nuclear emergencies - General principles and application to dicentric assay