This document specifies the liquid chromatography/tandem mass spectrometry method for the determination of desonide, 16α-hydroxyprednisolone, 16α-hydroxyprednisolone acetate, diflurasone, fluocinolone acetonide, desoximetasone, and paclitaxel in cosmetics. The principles of eleven glucocorticoids: lamethasone acetate, desonide 21-acetate, methylprednisolone acetate propionate, halobetasol propionate and betamethasone butyrate propionate, Reagents and materials, instruments and equipment, measurement procedures, result calculation, recovery rate and precision, etc. This document applies to water, lotion, cream (except wax-based), and essential oil cosmetics.
GB/T 40145-2021 Referenced Document
GB/T 24800.2-2009 Determination of 41 glucocorticoids in cosmetics by LC-MS-MS and TLC method
GB/T 6682 Water for analytical laboratory use.Specification and test methods
GB/T 40145-2021 history
2021GB/T 40145-2021 Determination of 11 glucocorticoids including desonide in cosmetics— Liquid chromatography-tandem mass spectrometry