GB/T 43544-2023
Oral care and cleaning products—Laboratory test method for inhibition rate of toothpastes to dental calculus (English Version)

Standard No.

GB/T 43544-2023

Language

Chinese, Available in English version

Release Date

2023

Published By

General Administration of Quality Supervision, Inspection and Quarantine of the People‘s Republic of China

Latest

GB/T 43544-2023

Introduction

1. Background and purpose of the standard

GB/T 43544-2023 "Laboratory test method for the inhibition rate of dental calculus by toothpaste for oral cleaning and care products" is a standard document proposed by the China Light Industry Federation and managed by the National Technical Committee for Standardization of Oral Care Products. This standard aims to standardize the laboratory test method for the inhibition rate of dental calculus by toothpaste and provide a scientific basis for quality assessment of oral care products.

2. Comparison of standard frameworks

Dimensions	GB/T 43544-2023	Related international standards	Other domestic standards
Test principle	Based on hydroxyapatite powder to simulate dental calculus formation, the inhibition rate is determined by calcium concentration.	Refer to ISO related oral care standard methods.	Coordinate with GB 5009.92-2016 Determination of calcium in food.
Reagent requirements	Analytical pure reagents, first-class water (GB/T 6682).	Adopt internationally recognized chemical reagent standards.	Meet the general reagent specifications of domestic laboratories.
Instruments and equipment	Special equipment such as magnetic stirring water bath, analytical balance, high-speed centrifuge, etc.	International advanced instrument standards.	Compatible with the technical requirements of domestic and imported equipment.

3. Practical Application Cases

Case Background:A toothpaste manufacturer needs to verify the inhibitory effect of its new product on dental calculus.

Test Steps:

1. Prepare toothpaste slurry solution and centrifuge to obtain supernatant.
2. Prepare hydroxyapatite suspension and add samples from different groups.
3. Simulate artificial saliva environment and react under constant pH conditions.
4. Determine calcium concentration and calculate inhibition rate.

Result Analysis:By comparing with the positive control group (5% sodium pyrophosphate solution) and the negative control group (water), calculate the inhibition rate of the sample and evaluate the product performance.

GB/T 43544-2023 Referenced Document

• GB 5009.92 National Food Safety Standard Determination of Calcium in Food

GB/T 43544-2023 history

• 2023 GB/T 43544-2023 Oral care and cleaning products—Laboratory test method for inhibition rate of toothpastes to dental calculus

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